![]() ![]() Most itching is resolved by slowing the infusion.Reactions are generally worse with the first few infusions and get better over time.These are usually mild and go away over a day or two.Common injection site reactions such as redness, swelling and itching.Reactions or side effects to SCIg include: This means that there is an extremely low (almost zero) chance of the transmission of blood borne viruses (such as Hepatitis B, Hepatitis C, HIV and Variant Creutzfeldt-Jakob disease (also called “mad cow disease”) via SCIg. Manufacturers also include steps in the processing of blood or plasma that inactivate or remove viruses. SCIg is made from plasma (the liquid part of blood), which comes from blood donors who are checked to make sure they are healthy and do not have certain infectious diseases. Push method - a manual method that does not require a pump, with the infusion pushed by hand through a syringe.Mechanical infusion pumps - spring loaded or battery powered.However, the outer edge of the thigh or back of the upper arm can also be used. Is administered at multiple injection sites according to personal preference, usually in the lower abdomen.Is associated with more consistent serum IgG levels due to frequent administration. ![]() Involves slow diffusion of IgG from subcutaneous tissue.Requires frequent administration (ranging from 1-3 times per week to once a fortnight) by patients or carers at home.Subcutaneous Immunoglobulin (SCIg) infusions are given by slowly injecting purified immunoglobulin into fatty tissue just underneath the skin. Replacing these antibodies helps to protect against infection and can prevent long term damage from ongoing infections, such as chronic lung disease. Immunoglobulins (commonly known as antibodies) are used to treat adults and children with primary immune deficiencies (PID), also known as inborn errors of immunity, and other medical conditions, who are unable to make enough of their own antibodies, or who have antibodies that don’t work properly.
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